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Journal Articles

Open Access

Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review)

Saizhi Jiang, Jamie L. Young, Kai Wang, Yan Qian, Lu Cai

Pages: 603-611 Published online on: 22 May 2020

c‑Abl‑mediated tyrosine phosphorylation of DNA damage response proteins and implications in important cellular functions (Review)

Ameer Ali Bohio, Ruoxi Wang, Xianlu Zeng, Xueqing Ba

Pages: 612-619 Published online on: 18 May 2020
Open Access

Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network

Daojun Hu, Boke Zhang, Miao Yu, Wenjie Shi, Li Zhang

Pages: 620-632 Published online on: 22 May 2020
Open Access

miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4

Yujing Fan, Kuanyu Wang

Pages: 633-642 Published online on: 18 May 2020
Open Access

Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation

Ayano Tada, Haruyuki Nakayama‑Imaohji, Hisashi Yamasaki, Miad Elahi, Tamiko Nagao, Hirofumi Yagi, Masao Ishikawa, Koji Shibuya, Tomomi Kuwahara

Pages: 643-650 Published online on: 07 May 2020
Open Access

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats

Zhi‑Peng Lin, Hui‑Li Lin, Xue‑Ping Yu, Yi‑Juan Zheng, Si‑Yu Cheng

Pages: 651-660 Published online on: 07 May 2020
Open Access

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang

Pages: 671-680 Published online on: 07 May 2020
Open Access

STAR mutations causing non‑classical lipoid adrenal hyperplasia manifested as familial glucocorticoid deficiency

Yuanyuan Luo, Ruojing Bai, Zhifang Wang, Xiaofan Zhu, Jingjing Xing, Xialian Li

Pages: 681-686 Published online on: 07 May 2020
Open Access

Anticancer effect of caudatin in diethylnitrosamine‑induced hepatocarcinogenesis in rats

Jie Song, Wenbo Ding, Bojia Liu, Dan Liu, Zhi Xia, Li Zhang, Li Cui, Yi Luo, Xiaobin Jia, Liang Feng

Pages: 697-706 Published online on: 07 May 2020
Open Access

Effects of dihydroartemisinin on the gut microbiome of mice

Yanyan Liu, Yanhong Yang, Yuting Lei, Lanxiang Yang, Xueying Zhang, Jian Yuan, Zili Lei

Pages: 707-714 Published online on: 20 May 2020
Open Access

Effects of human umbilical cord mesenchymal stem cells derived from exosomes on migration ability of endometrial glandular epithelial cells

Ying Feng, Fuliang Zhan, Yanying Zhong, Buzhen Tan

Pages: 715-722 Published online on: 07 May 2020
Open Access

Long non‑coding RNA FLVCR1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑30b‑3p

Weida Gao, Hongbin Li, Yang Liu, Yao Zhang, Hong Zhao, Fei Liu

Pages: 723-732 Published online on: 15 May 2020
Open Access

Syntenin regulates melanogenesis via the p38 MAPK pathway

Lijun Sun, Chunyan Guo, Liting Yan, Huijin Li, Jingying Sun, Xueping Huo, Xin Xie, Jun Hu

Pages: 733-738 Published online on: 07 May 2020
Open Access

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model

Weigang Cui, Chunli Sun, Yuqi Ma, Songtao Wang, Xianwei Wang, Yinghua Zhang

Pages: 739-750 Published online on: 18 May 2020
Open Access

Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture

Zhidong Zhou, Hejian Li, Hongchun Li, Jing Zhang, Kaiwen Fu, Cao Cao, Fumou Deng, Jun Luo

Pages: 751-762 Published online on: 20 May 2020
Open Access

Effects of sacral nerve electrical stimulation on 5‑HT and 5‑HT3AR/5‑HT4R levels in the colon and sacral cord of acute spinal cord injury rat models

Yi Zhu, Jie Cheng, Jichao Yin, Yujie Yang, Jiabao Guo, Wenyi  Zhang, Bing Xie, Haixia Lu, Dingjun Hao

Pages: 763-773 Published online on: 15 May 2020
Open Access

NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling

Shiqiang Zhang, Yun Yang, Yunwei Hua, Chen Hu, Yi Zhong

Pages: 774-782 Published online on: 18 May 2020
Open Access

Downregulation of microRNA‑106a‑5p alleviates ox‑LDL‑mediated endothelial cell injury by targeting STAT3

Ying Hu, Rong Xu, Yue He, Zhibo Zhao, Xudong Mao, Ling Lin, Jun Hu

Pages: 783-791 Published online on: 14 May 2020
Open Access

Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke

Sujuan Sun, Litao Li, Lipeng Dong, Jinming Cheng, Congying Zhao, Chu Bao, Hebo Wang

Pages: 792-802 Published online on: 14 May 2020
Open Access

Effects of miR‑195‑5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2

Xiaojie Liao, Zhuolin Zhou, Xiaoliu Zhang

Pages: 803-809 Published online on: 12 May 2020
Open Access

Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells

Qiong Wang, Wenwen Zhu, Geqiong Xiao, Mengyu Ding, Jian Chang, Hui Liao

Pages: 810-818 Published online on: 22 May 2020
Open Access

Expression and clinical value of SALL4 in renal cell carcinomas

Jianping Che, Pengfei Wu, Guangchun Wang, Xudong Yao, Junhua Zheng, Changcheng Guo

Pages: 819-827 Published online on: 22 May 2020
Open Access

Clinical characteristics and prognostic significance of TCGA and ACRG classification in gastric cancer among the Chinese population

Qiang Wang, Qi Xie, Yang Liu, Honghai Guo, Yingchun Ren, Jianke Li, Qun Zhao

Pages: 828-840 Published online on: 22 May 2020
Open Access

Downregulated miR‑29a promotes B cell overactivation by upregulating Crk‑like protein in systemic lupus erythematosus

Xinyu Shi, Lulu Ye, Shuqi Xu, Gangqiang Guo, Ziyi Zuo, Mengke Ye, Lejiang Zhu, Baoqing Li, Xiangyang Xue, Qiaoai Lin, Xiaokai Ding

Pages: 841-849 Published online on: 21 May 2020
Open Access

miR‑217‑5p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2

Menghai Zhu, Gang Chen, Yi Yang, Jiantao Yang, Bengang Qin, Liqiang Gu

Pages: 850-858 Published online on: 07 May 2020
Open Access

Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis

Xiaojie Chen, Yuanbo Pan, Mengxia Yan, Guanshui Bao, Xuhong Sun

Pages: 859-869 Published online on: 20 May 2020
Open Access

Adiponectin inhibits cardiac arrest/cardiopulmonary resuscitation‑induced apoptosis in brain by increasing autophagy involved in AdipoR1‑AMPK signaling

Yarong He, Bofu Liu, Peng Yao, Yuming Shao, Yanwei  Cheng, Jie  Zhao, Jiang Wu, Zhi Wei Zhao, Wen Huang, Theodore   A. Christopher, Bernard Lopez, Xinliang Ma, Yu Cao

Pages: 870-878 Published online on: 22 May 2020
Open Access

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

Jie Li, Chuanhua Gao, Shanshan Huang, Longteng Jin, Changzhong Jin

Pages: 879-885 Published online on: 18 May 2020
Open Access

TIM‑3 inhibits PDGF‑BB‑induced atherogenic responses in human artery vascular smooth muscle cells

Chong Lian, Zhecun Wang, Jiacong Qiu, Baohong Jiang, Junbing Lv, Rongzhou He, Ruiming Liu, Wen Li, Jinsong Wang, Shenming Wang

Pages: 886-894 Published online on: 21 May 2020
Open Access

Downregulation of miRNA‑328 promotes the angiogenesis of HUVECs by regulating the PIM1 and AKT/mTOR signaling pathway under high glucose and low serum condition

Yan Zou, Fei Wu, Qi Liu, Xian Deng, Rui Hai, Xuemei He, Xiangyu Zhou

Pages: 895-905 Published online on: 12 May 2020
Open Access

Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma

Lingling Chen, Ming Wang, Zefeng Lin, Mengyu Yao, Wanshun Wang, Shi Cheng, Binglin Li, Yu Zhang, Qingshui Yin

Pages: 906-914 Published online on: 22 May 2020
Open Access

Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy

Hao Zhang, Junyu Huo, Wanying Jiang, Qijun Shan

Pages: 915-925 Published online on: 14 May 2020
Open Access

miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth

Juan Peng, Jiang Jiang, Huizi Wang, Xinzi Feng, Xudong Dong

Pages: 926-938 Published online on: 22 May 2020
Open Access

Targeting protein palmitoylation decreases palmitate‑induced sphere formation of human liver cancer cells

Lee‑Won Chong, Chia‑Ling Tsai, Kou‑Ching Yang, Chen‑Chung Liao, Yi‑Chao Hsu

Pages: 939-947 Published online on: 22 May 2020
Open Access

High expression levels and localization of Sox5 in dilated cardiomyopathy

Yafeng Liu, Ben Jiang, Yide Cao, Wen Chen, Li Yin, Yueyue Xu, Zhibing Qiu

Pages: 948-956 Published online on: 22 May 2020
Open Access

Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R

Yuanyuan Cui, Yuting Li, Jiayi Ning, Yajing Mi, Xiaolong  Wang, Zhongying Qiu, Le Li, Xingchun Gou

Pages: 957-963 Published online on: 18 May 2020
Open Access

Comprehensive investigation of T and B cell receptor repertoires in an MC38 tumor model following murine anti‑PD‑1 administration

Lu Zhang, I‑Ming Wang, Nicolas Solban, Razvan Cristescu, Gefei Zeng, Brian Long

Pages: 975-985 Published online on: 22 May 2020
Open Access

Drug screening and identification of key candidate genes and pathways of rheumatoid arthritis

Yu‑Quan Shi, Wu‑Fang Qi, Chun‑Yu Kong

Pages: 986-996 Published online on: 21 May 2020
Open Access

Long non‑coding RNA‑based risk scoring system predicts prognosis of alcohol‑related hepatocellular carcinoma

Yue Luo, Jiaxiang Ye, Jiazhang Wei, Jinyan Zhang, Yongqiang Li

Pages: 997-1007 Published online on: 22 May 2020
Open Access

MicroRNA‑29a promotes the neural differentiation of rat neural stem/progenitor cells by targeting KLF4

Yunan Gao, Hu Qiao, Tianyu Zhong, Zhen Lu, Yuxia Hou

Pages: 1008-1016 Published online on: 22 May 2020
Open Access

TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p

Shanshan Li, Yixin Yin, Liping Yao, Ziyi Lin, Shengjun Sun, Jin Zhang, Xiaoyan Li

Pages: 1017-1025 Published online on: 18 May 2020
Open Access

Saikosaponin D inhibits autophagosome‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells

Ruoqiu Fu, Lin Zhang, Yuanyuan Li, Bin Li, Yue Ming, Zhiwei Li, Haiyan Xing, Jianhong Chen

Pages: 1026-1034 Published online on: 18 May 2020
Open Access

Klotho downregulation contributes to myocardial damage of cardiorenal syndrome in sepsis

Fei Yan, Yue Feng, Jin Chen, Jing Yan

Pages: 1035-1043 Published online on: 22 May 2020
Open Access

Comparison of neuronal death and expression of TNF‑α and MCT4 in the gerbil hippocampal CA1 region induced by ischemia/reperfusion under hyperthermia to those under normothermia

Taek Geun Ohk, Ji Hyeon Ahn, Young Eun Park, Tae‑Kyeong Lee, Bora Kim, Jae‑Chul Lee, Jun Hwi Cho, Joon Ha Park, Moo‑Ho Won, Choong‑Hyun Lee

Pages: 1044-1052 Published online on: 22 May 2020

Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease

Zongwen Wang, Lei Shen, Yue Wang, Shuqi Huang

Pages: 1053-1062 Published online on: 20 May 2020

Antihypertensive drug telmisartan inhibits cell proliferation of gastrointestinal stromal tumor cells in vitro

Hideki Kobara, Shintaro Fujihara, Hisakazu Iwama, Takanori Matsui, Ayako Fujimori, Taiga Chiyo, Shi Tingting, Nobuya Kobayashi, Noriko Nishiyama, Tatsuo Yachida, Tomoko Tadokoro, Kyoko Oura, Joji Tani, Koji Fujita, Takako Nomura, Hirohito Yoneyama, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Hirohito Mori, Tsutomu Masaki

Pages: 1063-1071 Published online on: 14 May 2020

Role of DNA damage in the progress of chronic tubule‑interstitial injury

Linxiao Sun, Xiandong Zhu, Jiao Luo, Cheng Wang, Bicheng Chen

Pages: 1081-1089 Published online on: 14 May 2020
Open Access

[Corrigendum] Protective effects of exendin‑4 on hypoxia/reoxygenation‑induced injury in H9c2 cells

Kai Lu, Guanglei Chang, Lin Ye, Peng Zhang, Yong Li, Dongying Zhang

Pages: 1090-1090 Published online on: 18 May 2020
Open Access

Primary open angle glaucoma genetics: The common variants and their clinical associations (Review)

Alexandra Trivli, Maria I. Zervou, George N. Goulielmos, Demetrios A. Spandidos, Efstathios T. Detorakis

Pages: 1103-1110 Published online on: 09 June 2020
Open Access

Identification of geraldol as an inhibitor of aquaporin‑4 binding by NMO‑IgG

Jie Wang, Shuai Wang, Meiyan Sun, Huijing Xu, Wei Liu, Deli Wang, Lei Zhang, Yan Li, Jiaming Cao, Fang Li, Miao Li

Pages: 1111-1118 Published online on: 04 June 2020
Open Access

Cyclic stretch promotes the ossification of ligamentum flavum by modulating the Indian hedgehog signaling pathway

Rui Gao, Changgui Shi, Chengwei Yang, Yin Zhao, Xiongsheng Chen, Xuhui Zhou

Pages: 1119-1128 Published online on: 02 June 2020
Open Access

Xanthan gum protects temporomandibular chondrocytes from IL‑1β through Pin1/NF‑κB signaling pathway

Fang Yuan, Jian‑Li Xie, Ke‑Yin Liu, Jian‑Liang Shan, Yu‑Gang Sun, Wang‑Gui Ying

Pages: 1129-1136 Published online on: 15 June 2020
Open Access

Echinacoside promotes the proliferation of human renal tubular epithelial cells by blocking the HBX/TREM2‑mediated NF‑κB signalling pathway

Yufan Zhang, Qinfang Wu, Limin Zhong, Lei Wang, Dongwei Gong

Pages: 1137-1144 Published online on: 02 June 2020
Open Access

Transcription box‑3 protects human umbilical vein endothelial cells in a high‑glucose environment through sirtuin 1/AKT signaling

Zhanjiang Yu, Wei Zhang, Xiankun Zhang, Donghui Xu, Na Wang

Pages: 1145-1154 Published online on: 15 June 2020
Open Access

Identification of co‑expression modules and hub genes of retinoblastoma via co‑expression analysis and protein‑protein interaction networks

Yukun Mao, Qingbin Nie, Yang Yang, Gengsheng Mao

Pages: 1155-1168 Published online on: 27 May 2020
Open Access

Superior CKIP-1 sensitivity of orofacial bone-derived mesenchymal stem cells in proliferation and osteogenic differentiation compared to long bone-derived mesenchymal stem cells

Xin Huang, Bingkun Cheng, Wen Song, Le Wang, Yanyuan Zhang, Yan Hou, Yu Song, Liang Kong

Pages: 1169-1178 Published online on: 15 June 2020
Open Access

Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts

Lin Tao, Sichao Zhao, Zhengbo Tao, Kaicheng Wen, Siming Zhou, Wacili Da, Yue Zhu

Pages: 1179-1186 Published online on: 15 June 2020
Open Access

TBOPP enhances the anticancer effect of cisplatin by inhibiting DOCK1 in renal cell carcinoma

Wei Zhang, Xiaoxiao Zheng, Shangzhi Xie, Shufen Zhang, Jiayan Mao, Ying Cai, Xuemei Lu, Wei Chen, Haibin Ni, Liping Xie

Pages: 1187-1194 Published online on: 16 June 2020
Open Access

Knockdown of long non‑coding RNA AK094629 attenuates the interleukin‑1β induced expression of interleukin‑6 in synovium‑derived mesenchymal stem cells from the temporomandibular joint

Jiaxin Jia, Jiadong Sun, Wenting Liao, Lingling Qin, Kai Su, Yiqing He, Jiaqiang Zhang, Ronchung Yang, Zhiguang Zhang, Yangpeng Sun

Pages: 1195-1204 Published online on: 28 May 2020
Open Access

Effect of IL‑7 on Th17 cell responses in a mouse model of neutrophilic asthma

Xiaobo Zhang, Min Zhang, Min Jiang, Guangmin Nong

Pages: 1205-1212 Published online on: 27 May 2020
Open Access

Molecular mechanism of gossypol mediating CCL2 and IL‑8 attenuation in triple‑negative breast cancer cells

Samia S. Messeha, Najla O. Zarmouh, Patricia Mendonca, Carolyn Cotton, Karam F.A. Soliman

Pages: 1213-1226 Published online on: 15 June 2020
Open Access

Bioinformatics analysis of small RNAs in Helicobacter pylori and the role of NAT‑67 under tinidazole treatment

Jie Du, Wang Zhang, Xiao‑Hui Li, Yuan‑Jian Li

Pages: 1227-1234 Published online on: 15 June 2020
Open Access

Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy

Yang-Gyu Park, Jawun Choi, Jae-Won Seol

Pages: 1235-1242 Published online on: 27 May 2020
Open Access

Prognostic value of MYD88 L265P mutation in diffuse large B cell lymphoma via droplet digital PCR

Jing Niu, Zhiping Ma, Aijiang Nuerlan, Sijing Li, Wenli Cui, Haixia Gao, Gulinaer Abulajiang, Wei Zhang, Xinxia Li

Pages: 1243-1256 Published online on: 27 May 2020
Open Access

Quantitative proteomic characterization of microvesicles/exosomes from the cerebrospinal fluid of patients with acute bilirubin encephalopathy

Ning Tan, Shuiwang Hu, Zhen Hu, Zhouli Wu, Bin Wang

Pages: 1257-1268 Published online on: 28 May 2020
Open Access

Detection of chromosomal abnormalities in spontaneous miscarriage by low‑coverage next‑generation sequencing

Fen‑Xia Li, Mei‑Juan Xie, Shou‑Fang Qu, Dan He, Long Wu, Zhi‑Kun Liang, Ying‑Song Wu, Fang Yang, Xue‑Xi Yang

Pages: 1269-1276 Published online on: 03 June 2020
Open Access

MicroRNA-196a promotes cell proliferation and inhibits apoptosis in human ovarian cancer by directly targeting DDX3 and regulating the PTEN/PI3K/AKT signaling pathway

Jie Ni, Li Chen, Li Ling, Mengfei Wu, Qiongzhen Ren, Weipei Zhu

Pages: 1277-1284 Published online on: 15 June 2020
Open Access

A novel variant in AIRE causing a rare, non‑classical autoimmune polyendocrine syndrome type 1

Wen‑Bin Zheng, Lu‑Jiao Li, Di‑Chen Zhao, Ou Wang, Yan Jiang, Wei‑Bo Xia, Mei Li

Pages: 1285-1294 Published online on: 12 June 2020
Open Access

Overexpression of ATG4a promotes autophagy and proliferation, and inhibits apoptosis in lens epithelial cells via the AMPK and Akt pathways

Chufan Yan, Jiangyue Zhao, Yu Qin, Fangkun Zhao, Liyang Ji, Jinsong Zhang

Pages: 1295-1302 Published online on: 02 June 2020
Open Access

Long non-coding RNA expression profiling following treatment with resveratrol to improve insulin resistance

Linyi Shu, Guangsen Hou, Hang Zhao, Wenli Huang, Guangyao Song, Huijuan Ma

Pages: 1303-1316 Published online on: 11 June 2020
Open Access

Age‑dependent alterations in the immunoreactivity of macrophage inflammatory protein‑3α and its receptor CCR6 in the gerbil hippocampus

Ji Hyeon Ahn, Joon Ha Park, Tae‑Kyung Lee, Go Eun Yang, Myoung Cheol Shin, Jun Hwi Cho, Moo‑Ho Won, Choong‑Hyun Lee

Pages: 1317-1324 Published online on: 09 June 2020
Open Access

Salvianolic acid B attenuates renal interstitial fibrosis by regulating the HPSE/SDC1 axis

Yang Hu, Man Wang, Yunzheng Pan, Qingju Li, Li Xu

Pages: 1325-1334 Published online on: 15 June 2020
Open Access

Diosmetin alleviates hypoxia‑induced myocardial apoptosis by inducing autophagy through AMPK activation

Qijun Si, Yujie Shi, Dandan Huang, Na Zhang

Pages: 1335-1341 Published online on: 16 June 2020
Open Access

Effects of Sirt3‑autophagy and resveratrol activation on myocardial hypertrophy and energy metabolism

Hai‑Ning Wang, Ji‑Lin Li, Tan Xu, Huai‑Qi Yao, Gui‑Hua Chen, Jing Hu

Pages: 1342-1350 Published online on: 28 May 2020
Open Access

Troxerutin attenuates oxygen‑glucose deprivation and reoxygenation‑induced oxidative stress and inflammation by enhancing the PI3K/AKT/HIF‑1α signaling pathway in H9C2 cardiomyocytes

Zhang‑Ping Yu, Han‑Qiao Yu, Jun Li, Chao Li, Xian Hua, Xiao‑Sheng Sheng

Pages: 1351-1361 Published online on: 03 June 2020
Open Access

Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma

Xuefeng Wang, Shuang Liu, Zhengkai Shao, Penghai Zhang

Pages: 1362-1372 Published online on: 03 June 2020
Open Access

RP105 plays a cardioprotective role in myocardial ischemia reperfusion injury by regulating the Toll‑like receptor 2/4 signaling pathways

Weiling Huang, Jian Yang, Chao He, Jun Yang

Pages: 1373-1381 Published online on: 16 June 2020
Open Access

Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang

Pages: 1382-1390 Published online on: 27 May 2020
Open Access

Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats

Xiaona Zhang, Xiushuang Fan, Fan Li, Jinpeng Qiu, Yang Zhang

Pages: 1391-1399 Published online on: 16 June 2020
Open Access

Effects of an ethyl acetate extract of Daphne altaica stem bark on the cell cycle, apoptosis and expression of PPARγ in Eca‑109 human esophageal carcinoma cells

Murat Kizaibek, Ayixiamuguli Wubuli, Zhengbing Gu, Didar Bahetjan, Lazzat Tursinbai, Kamishbek Nurhamit, Bin Chen, Jing Wang, Omirshat Tahan, Peng Cao

Pages: 1400-1408 Published online on: 27 May 2020
Open Access

The gonadal expression pattern of lipocalin‑2 and 24p3 receptor is modified in the gonads of the offspring of obese rats

Elsa De La Chesnaye, Leticia Manuel‑Apolinar, Leticia Damasio, Edgar Castrejón, Rebeca López‑Ballesteros, María Cristina Revilla‑Monsalve, Juan Pablo Méndez

Pages: 1409-1419 Published online on: 12 June 2020
Open Access

Role of endoplasmic reticulum oxidase 1α in H9C2 cardiomyocytes following hypoxia/reoxygenation injury

Lina Lai, Yue Liu, Yuanyuan Liu, Ni Zhang, Shilu Cao, Xiaojing Zhang, Di Wu

Pages: 1420-1428 Published online on: 09 June 2020
Open Access

Schizophrenia‑associated microRNA‑148b‑3p regulates COMT and PRSS16 expression by targeting the ZNF804A gene in human neuroblastoma cells

Shanshan Wu, Pengjie Wang, Ran Tao, Pengbo Yang, Xiaorui Yu, Ye Li, Qiuya Shao, Fayi Nie, Jing Ha, Rui Zhang, Ye Tian, Jie Ma

Pages: 1429-1439 Published online on: 15 June 2020
Open Access

TAK‑242 exerts a neuroprotective effect via suppression of the TLR4/MyD88/TRIF/NF‑κB signaling pathway in a neonatal hypoxic‑ischemic encephalopathy rat model

Lijun Jiang, Zhenxing Xu, Hui Li, Mingfu Wu, Fudong Wang, Shunying Liu, Jianlan Tao, Xing Feng

Pages: 1440-1448 Published online on: 11 June 2020
Open Access

lncRNA MALAT1 modulates cancer stem cell properties of liver cancer cells by regulating YAP1 expression via miR‑375 sponging

Liying Zhao, Guohua Lou, Aichun Li, Yanning Liu

Pages: 1449-1457 Published online on: 29 May 2020
Open Access

Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats

Wen Yuan, Heng‑Ya Song, Jie Xiong, Wan‑Li Jiang, Gan‑Jun Kang, Jie Huang, Song‑Ping Xie

Pages: 1458-1466 Published online on: 15 June 2020
Open Access

Cytoprotective role of humanin in lens epithelial cell oxidative stress‑induced injury

Hao Yang, Yilei Cui, Yelei Tang, Xiajing Tang, Xiaoning Yu, Jiayue Zhou, Qichuan Yin, Xingchao Shentu

Pages: 1467-1479 Published online on: 02 June 2020
Open Access

Association between levels of aquaporin 3 in the placenta and adiponectin in the umbilical cord blood with gestational diabetes mellitus and pregnancy outcome

Chunqi Zhang, Yanxia Li, Jia Wang, Chunmei Liu, Yan Chen

Pages: 1498-1506 Published online on: 12 June 2020
Open Access

Propofol‑induced miR‑125a‑5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B

Juan Zeng, Yu‑Kun Li, Fei‑Fei Quan, Xin Zeng, Chang‑Ye Chen, Tian Zeng, Juan Zou, Wen‑Juan Tong

Pages: 1507-1517 Published online on: 11 June 2020
Open Access

Transcriptomic changes involved in the dedifferentiation of myofibroblasts derived from the lung of a patient with idiopathic pulmonary fibrosis

Kenichi Suzuki, Jun‑Dal Kim, Keita Ugai, Shuichi Matsuda, Hideki  Mikami, Kento  Yoshioka, Jun Ikari, Masahiko Hatano, Akiyoshi  Fukamizu, Koichiro Tatsumi, Yoshitoshi Kasuya

Pages: 1518-1526 Published online on: 10 June 2020
Open Access

Tubeimoside‑1 induces apoptosis in human glioma U251 cells by suppressing PI3K/Akt‑mediated signaling pathways

Li‑Juan Cao, Hai‑Tang Xie, Zhong‑Xia Chu, Yue Ma, Ming‑Ming Wang, Zhuang Shi

Pages: 1527-1535 Published online on: 11 June 2020
Open Access

Deficiency of PDK1 in osteoclasts delays fracture healing and repair

Dongliang Xiao, Quan Zhou, Yiguang Bai, Baichuan Cao, Qiong Zhang, Gaofeng Zeng, Shaohui Zong

Pages: 1536-1546 Published online on: 03 June 2020
Open Access

Non‑invasive prenatal diagnosis of thalassemia through multiplex PCR, target capture and next‑generation sequencing

Xu Yang, Yanchou Ye, Dongmei Fan, Sheng Lin, Ming Li, Hongying Hou, Jun Zhang, Xuexi Yang

Pages: 1547-1557 Published online on: 15 June 2020
Open Access

Siva‑1 regulates multidrug resistance of gastric cancer by targeting MDR1 and MRP1 via the NF‑κB pathway

Fan‑Biao Kong, Qiao‑Ming Deng, Hong‑Qiang Deng, Chen‑Cheng Dong, Lei Li, Chun‑Gang He, Xiao‑Tong Wang, Sheng Xu, Wei Mai

Pages: 1558-1566 Published online on: 03 June 2020
Open Access

Key miRNAs associated with memory and learning disorder upon exposure to sevoflurane determined by RNA sequencing

Huaqin Sun, Hongyi Hu, Xiaoping Xu, Tao Tao, Zhehao Liang

Pages: 1567-1575 Published online on: 01 June 2020
Open Access

Quantitative determination of human serum testosterone via isotope dilution ultra‑performance liquid chromatography tandem mass spectrometry

Guang Sun, Jinmei Xue, Liuxu Li, Xue Li, Yaqiong  Cui, Bin Qiao, Dianjun Wei, Huiqiang Li

Pages: 1576-1582 Published online on: 15 June 2020

Cholestatic models induced by lithocholic acid and α‑naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signaling

Gangming Xu, Manyun Dai, Xiuting Zheng, Hante Lin, Aiming Liu, Julin Yang

Pages: 1583-1593 Published online on: 03 June 2020

miR‑200c‑3p regulates the proliferation and apoptosis of human trabecular meshwork cells by targeting PTEN

Yifei Shen, Yin Zhu, Fei Rong

Pages: 1605-1612 Published online on: 01 June 2020

MicroRNA‑133b aggravates atherosclerosis by activating the Notch signaling pathway

Baizhi Han, Tao Li, Shiliang Zheng

Pages: 1621-1630 Published online on: 11 June 2020

Downregulation of folate receptor α contributes to homocysteine‑induced human umbilical vein endothelial cell injury via activation of endoplasmic reticulum stress

Jie Cui, Cheng Cao, Huan Hu, Hao Zhang, Yujing Yang, Luqiao Wang, Xiao Huang, Ping Li

Pages: 1631-1638 Published online on: 02 June 2020

Transcription factor AP‑2α negatively regulates thymic stromal lymphopoietin expression in respiratory syncytial virus infection

Jia He, Qian Cao, Dan‑Dan Feng, Jia‑He Chen, Guo‑Ping Zhou

Pages: 1639-1646 Published online on: 28 May 2020

Melatonin inhibits the endoplasmic reticulum stress‑induced, C/EBP homologous protein‑mediated pathway in acute pancreatitis

Qian Zhao, Hui Zhang, Jie Wu, Xiangyin Lv, Xianghong Jin, Jianwen Hu

Pages: 1647-1655 Published online on: 10 June 2020

SB203580 protects against inflammatory response and lung injury in a mouse model of lipopolysaccharide‑induced acute lung injury

Guirong Li, Youai Dai, Jianxin Tan, Jian Zou, Xiaowei Nie, Zhenkun Yang, Jingjing Zhao, Xusheng Yang, Jingyu Chen

Pages: 1656-1662 Published online on: 04 June 2020
Open Access

[Corrigendum] Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation

Fu Hua, Ye Tian, Yingchun Gao, Changhua Li, Xiaoping Liu

Pages: 1663-1663 Published online on: 29 May 2020
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August-2020
Volume 22 Issue 2

Print ISSN: 1791-2997
Online ISSN: 1791-3004
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